Question

Which steps of glycolysis are irreversible?

Answer 1

Glycolysis

It is the process occuring in the cytoplasm in which ATP through cellular respiration by breaking down glucose molecules, as a result of which two pyruvate molecules are produced.

Irreversible steps of glycolysis

1. Glycolysis involves a total of 10 steps out of which 7 are reversible and 3 are irreversible.
2. Steps 1, 3, and 10 are irreversible.
3. In step 1, Glucose is converted to glucose 6-phosphate in the presence of the enzyme hexokinase.
4. In step 3, fructose 6-phosphate is converted to fructose 1,6-biphosphate in the presence of the enzyme phosphofructokinase.
5. In step 10, phosphoenolpyruvate is converted to pyruvate in the presence of the enzyme pyruvate kinase.