Question

Who proposed the sandwich model of the plasma membrane?

• A. Davson and Danielli
• B. Robertson
• C. Singer and Nicolson
• D. Benson

Answer 1

The correct option is A

Davson and Danielli

The correct option is A.

Explanation of correct option:

1. In 1935, the Sandwich or Lamellar Model or bimolecular leaflet model was suggested by Danielli and Davson.
2. According to which plasma membrane contains a phospholipid layer and in between two layers of protein like a sandwich in P-L-L-P structure with nonpolar tails of the lipid bilayer in the center.

Explanation of incorrect options:

Option B:

1. Robertson's Unit membrane model in 1959 A.D proposed that a biomembrane is a lipoprotein and a three-layer (trilaminar) structure surrounded by a dense protein inside and outside.

Option C:

1. Singer and Nicolson 1979 proposed Fluid Membrane Mosaic Model, in a lipid bilayer in which proteins are embedded in it.
2. The two-dimensional liquid restricts the lateral diffusion of the membrane.
3. It is the most acceptable model of plasma membrane.

Option D:

1. In 1966, Benson studied chloroplast membrane and proposed Benson's model according to which the lipid and protein form hydrophobic association.
2. The charged phospholipid lies on the surface and binds with the ions and the non-polar hydrophobic tail lies the interior side of the protein.

Final answer: Davson and Danielli proposed the sandwich model of the plasma membrane