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Carbylamine Test

Why does gluc...

Question

Why does glucose does not undergo Schiff's test?

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Solution

Glucose contains an aldehyde group in its open structure but forms a cyclic acetal structure(also called pyranose). This structure is quite stable and is not broken down by Schiff's reagent which is a weak base. Hence, it does not form hydrazone giving a negative Schiff's test

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