Carbylamine reaction – The carbylamine reaction (also known as the Hoffmann isocyanide synthesis) is the reaction of a primary amine, chloroform, and base to produce an isocyanide. Dichlorocarbene serves as an intermediary in the conversion. It’s employed in the production of secondary amines.
Sandmeyer reaction – The Sandmeyer Reaction is an important step in aromatic chemistry because it allows for substitution patterns that are impossible to achieve by direct replacement. The Schiemann Reaction, which is linked to fluorination, can be used.