Differentiate between intrinsic and extrinsic protein

Intrinsic protein

  • Intrinsic protein includes those proteins that are embedded within the plasma membrane.
  • Intrinsic protein are embedded in the plasma membrane partially or completely.
  • They are more hydrophobic.
  • They function as carrier proteins, enzymes and permeases.

    Extrinsic proteins

  • They are present in the surface of the plasma membrane
  • They are more hydrophilic and less hydrophobic
  • They function as receptors and antigens
  • Example are erythrocyte spectrin.

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