The nucleolus is just a part of the nucleus. The nucleus is the main part of the cell while the nucleolus is part of the nucleus itself.
- The nucleus is a membrane-bound organelle that is found in multi-celled organisms or eukaryotes while the nucleolus is the sub-organelle.
- The nucleus is membrane-bound while the nucleolus is non-membrane bound.
- The nucleus contains DNA while the nucleolus contains RNA.
- Nucleus contains DNA but nucleolus contains RNA.