The pancreas is an abdominal organ located behind the stomach and surrounded by spleen, liver and small intestine. It is a vital part of the digestive system and is responsible for regulating blood sugar levels.
There are four main hormones are generated by the endocrine pancreas they are, glucagon, insulin, somatostatin and pancreatic Polypeptide.
Several hours after a meal, the blood glucose levels in the body are low. This signals the pancreas to secrete glucagon, which signals the liver and muscle cells to convert the glycogen back to glucose, which is then readily absorbed by the other cells to produce energy. This loop continually functions, ensuring that the body’s glucose levels never drop too low.
When the body digests food rich in carbohydrates, glucose is released into the bloodstream. This leads to an increase in blood glucose levels in the body. Consequently, the pancreas sends signals that direct all the cells in the body to take in the glucose. Most of this glucose is used up to provide energy to the cells. The excess glucose in the bloodstream is converted into glycogen and absorbed by the liver and muscle cells to be used later.
Somatostatin also called GHIH (growth hormone inhibiting hormone) helps to regulate blood glucose and/or salt balance. Pancreatic Polypeptide It is a polypeptide which is secreted by the pancreatic cells. Protein is a powerful stimulus for its development. The gastric and biliary secretion and motility of the GI tract are affected by this polypeptide