Oestrogen and testosterone are steroid hormones, and they most likely bind to

Steroid hormones are lipophilic in nature. The lipids present in the cell membranes do not prohibit the entry of lipophilic molecules in the cell. Hence, steroid hormones easily diffuse through the cell membrane. When they enter the cell, they either bind to the cytoplasmic receptors or nucleic receptors to produce their effects.

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