The disease polio affects the Central Nervous System
How polio affects CNS?
A polio infection often damages or destroys many of these motor neurons. To compensate for the resulting neuron shortage, the remaining neurons sprout new fibres, and the surviving motor units enlarge. The virus enters the central nervous system, preferentially infecting and destroying motor neurons, leading to muscle weakness and acute flaccid paralysis. The poliovirus attacks specific neurons in the brain stem and spinal cord.