What is pyruvate?

Pyruvate is considered to be one of the important molecules which is found at the intersection of the multiple biochemical pathways. It is one of the end products of glycolysis which is transported to the mitochondria in the participation of the citric acid cycle.

Pyruvate undergoes fermentation to produce lactate in the absence of the oxygen. The regeneration of glucose is possible with pyruvate as well as with lactate. Anabolic synthesis of fatty acids and amino acids involves pyruvate.

There are two possible ways in which pyruvate can generate and they are:

  • Through the glycolytic pathway
  • Through metabolism of amino acids

The structure of pyruvate is based on the pyruvic acid as it is the conjugate base of this acid. It contains three carbon atoms, a carboxylic acid group, and a ketone functional group. The structure contains an a-carbon which is the second carbon atom in the structure and it is so-called because it is close to the main functional group.

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