In comparison to other minerals, calcium is the most abundant in our bodies. It is an important nutrient for the growth and maintenance of healthy bones and teeth. It also aids in the proper functioning of the heart, nerves, muscles, and other body organs.
Hypocalcemia, or calcium deficiency, does not occur immediately because our bones store the necessary amount of calcium in our bodies. Calcium deficiency is linked to a variety of diseases and conditions, including osteoporosis, diabetes, hypertension, cardiovascular disease, colon cancer, kidney stones, and weight control.
- Hypocalcaemia Tetany is the spontaneous tonic muscle contractions due to increased neuronal excitability that occurs as a result of low ECF calcium concentration that reduces the threshold for excitation of the neural tissue.
- Extracellular calcium and magnesium are thought to affect the local electric field of the membrane near ion channels such that hypocalcemia or hypomagnesemia reduce the amount of depolarization necessary to induce an increase in sodium conductance and depolarize nerve cells.
Why Calcium difficiency occurs?
Difficiency of calcium is due to
- Vitamin D mainly helps in the Ca/P balance of body fluids. It increases absorption of calcium from the intestines, so it is necessary for formation of healthy bones and teeth.
- Deficiency of Vitamin D causes an increased loss of calcium ions in urine; thus, calcium ions get deposited in the bones. This causes rickets in children and osteomalacia in pregnant woman.