Cushing’s syndrome is caused by an overabundance of corticosteroids in the body. The major cause of excessive ACTH (adrenocorticotropic hormone) activity in the pituitary gland. The adrenal gland produces corticosteroids in response to ACTH. As a result, too much ACTH equals too many corticosteroids.
Symptoms of cushing’s syndrome
Cushing’s syndrome can cause problems in various parts of the body. One of the most common symptoms is weight gain. High cortisol levels cause fat redistribution, particularly to the stomach and chest, as well as a rounding of the face.
The following are some other typical signs and symptoms,
- Easy bruising
- High blood pressure
- Thinning of the skin
- Excessive pink or purple stretch marks known as striae
- Changes or interruption in menstrual periods
- Muscle weakness