Aspirin Uses

What is Aspirin?

Aspirin is the prototype analgesic , antipyretic and anti – inflammatory drug . It is indicated for dysmenorrhoea , headache , pyrexia and transient musculoskeletal pain.

Aspirin may contribute to the formation of stomach ulcers and bleeding. People who are allergic to aspirin and those with a history of nasal polyps, asthma or rhinitis may experience breathing difficulty and a stuffy nose. Aspirin is widely used for secondary prevention in patients with established coronary, cerebrovascular, or peripheral arterial disease.

Table of Contents

• Aspirin
• Recommended Videos
• Aspirin Structure
• Therapeutic Uses of Aspirin
• Aspirin Side Effects
• Frequently Asked Questions – FAQs

Aspirin

Aspirin is the oldest and still the most widely used antiplatelet agent. Aspirin exerts its antithrombotic effect by irreversibly inhibiting platelet cyclooxygenase through acetylation of serine at position 529 leading to steric hindrance of substrates for the enzymes.

Aspirin is the prototype analgesic, antipyretic and anti-inflammatory drug. It is indicated for dysmenorrhoea, headache, pyrexia and transient musculoskeletal pain. Aspirin is usually given by mouth and is rapidly absorbed from both the stomach and the ileum.

Recommended Videos

Aspirin Structure

Aspirin has a range of benefits, from relieving discomfort to minimising the risk of serious conditions such as cardiac attacks and strokes. Aspirin is a common drug. It appears in many types, such as capsules, water-dissolved tablets, powders, and oral gels.

Aspirin (acetylsalicylic acid) is used in the treatment of cardiovascular disease and as an analgesic / anti-inflammatory drug. About four decades earlier, the discovery that thrombocytopenia-inducing agents decreased metastases led to the study of aspirin as an anticancer treatment, with fibrosarcoma metastasis greatly diminished by aspirin in animal models.

The structure of aspirin is given below.

Therapeutic Uses of Aspirin

Aspirin (acetylsalicylic acid) is a medical medication that is used to alleviate irritation or inflammation. It is a non-steroidal anti-inflammatory drug.

It is also used for blood clots, heart attacks, strokes, and bowel cancer prevention. However, while some studies have shown that aspirin can decrease the probability of heart attacks and cancer of the intestines, stomach, and oesophagus, clinicians are also urged to exert caution when using aspirin as a preventive measure, as it can increase the risk of gastrointestinal bleeding and harm.

Before taking aspirin, persons with renal failure, liver damage or haemophilia should see a specialist. Some people use aspirin to get high, or by deliberately taking more than the prescribed dosage as an act of self-harm.

Aspirin will increase the likelihood that the liver, small intestine, and brain will bleed. There is normally a membrane that protects the lining of your intestine and gut from the acid in your stomach. It will eventually affect this layer if aspirin is used at high doses and for a long time. This injury will contribute to bleeding. The normal repair of broken blood vessels and increasing the risk of bleeding in the brain will also be impaired by the use of aspirin to avoid blood clots.

Aspirin Side Effects

Aspirin may theoretically interfere with other drugs that can change their effects or raise the risk of side effects, including certain alternative and herbal medicines.

• When given in regular doses, a side effect is an unintended reaction to a drug. There can be moderate or serious, acute or lifelong side effects.
• Long-term therapy provides an antiplatelet effect with low doses of aspirin, typically 75 mg, which ensures it makes the blood less acidic and can avoid the formation of blood clots.
• Aspirin will typically alleviate discomfort, minimise elevated temperatures (fever) and decrease swelling at high doses of 300 mg.
• Aspirin must not be administered to children under 16 years of age unless a doctor has recommended it to treat a particular illness. This is because there is a theoretical connexion in children between aspirin and Reye ‘s syndrome. Reye ‘s syndrome is a very rare and potentially deadly illness.
• After heart surgery or to treat Kawasaki disease, aspirin can also be recommended for infants. But without medical care, it can not be issued to someone under 16 years old.
• If you drink alcohol while taking aspirin, the chance of bleeding in the stomach may be greater, so you may want to consider limiting how much you drink or totally banning alcohol.