Difference Between Electrophile and Nucleophile

The chemical reactions happening between electron donors and acceptors are described by concepts like electrophile and nucleophile. These are the most important concepts in organic chemistry. They have replaced cationoid and anionoid terms and in were introduced in the year 1933.

Electrophile:

The term electrophile can be split into “electro” derived from electron and “phile” which means loving. They are electron deficient and hence electrons loving. They are positively charged or neutrally charged. They attract electrons. Movement of electrons depends on the density. They move from high density area to low density area.They undergo electrophilic addition and electrophilic substitution reactions. Electrophile is also called as Lewis acid.

Nucleophile:

The term nucleophile can be split into “nucleo” derived from nucleus and “phile” which means loving. They are electron rich and hence nucleus loving. They are negatively charged or neutrally charged. They donate electrons. Movement of electrons depends on the density. They move from low density area to high density area.They undergo nucleophilic addition and nucleophilic substitution reactions. Nucleophile is also called as Lewis base.

To make you understand how electrophile and nucleophile are different from each other, here are the some of the major differences between atom and ion:

Difference between Electrophile and Nucleophile

ELECTROPHILE

NUCLEOPHILE

Also called as Lewis acid

Also called as Lewis base

They are positively charged / neutral

They are negatively charged / neutral

They undergo electrophilic addition and electrophilic substitution reactions

They undergo nucleophilic addition and nucleophilic substitution reactions

Electron deficient

Electron rich

It accepts pair of electron to form covalent bond

It donates pair of electron to form covalent bond

All carbocations

All carboanions

Example: Hydronium ion

Example: Chloride ion

These were some of the important difference between nucleophile and electrophile. To know differences between other topics in chemistry you can register to BYJU’S or download our app for simple and interesting content. India’s largest k-12 learning app with top notch teachers from across the nation with excellent teaching skills. Find notes, question papers for other subjects like Mathematics, Physics, Biology and various competitive exams as well. Enjoy learning with great experience. Learning is no more boring with BYJU’S.

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Histamines stimulate secretion of pepsin and hydrochloric acid in the stomach and excess of it can lead to acidity. They are also responsible for nasal congestion associated with common cold and allergic response to pollen.A person having an allergic problem takes ‘Brompheniramine’ which is an antihistamine.
Which of the following is correct about level of secretion of hydrochloric acid in the stomach of the person after consuming ‘Brompheniramine’?