Discontinuous Synthesis of DNA Occurs in One Strand, because

  1. The length of the DNA molecule synthesised is very long
  2. It is a more effective method
  3. DNA-dependent DNA polymerase catalyses polymerisation only in one direction (5′ to 3′)
  4. DNA ligase must be involved

The correct answer is C) DNA-dependent DNA polymerase catalyses polymerisation only in one direction (5′ to 3′).

DNA-dependent DNA polymerase catalyses polymerisation only in one direction (5′ to 3′). This produces extra complications at the replication fork. As a result, replication is continuous solely on one strand (3′ → 5′) and discontinuous on the other (5′ → 3′). Later, the DNA ligase enzyme joins the discontinuously synthesised fragments.

Therefore, “DNA-dependent DNA polymerase catalyses polymerisation only in one direction (5′ to 3′)” is the right response.

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