TFA Formula

TFA stands for Trifluoroacetic acid which is also known as 2,2,2-trifluoracetic acid is an organofluorine compound. The chemical formula of TFA is CF3CO2H. It is a very strong acid finding applications in organic and inorganic chemistry as it is highly acidic. It is a colourless and odourless liquid.

The property value of hydrogen bond donor and hydrogen bond acceptor is 1 and 5 respectively. Trifluoroacetic acid is synthesised by treating the acetyl chloride in electrochemical fluorination.

Structure Of TFA Formula

TFA Formula

Properties Of TFA Formula

IUPAC name 2,2,2-trifluoracetic acid
Chemical formula CF3CO2H
Molecular weight 114.023 g/mol
Density 1.489 g.m.L-1
Melting point -15.4℃
Boiling point 72.4℃
Enthalpy of vapourisation 33 kJ/mol

Applications Of TFA

  • TFA is used as a precursor to produce fluorinate compounds like fluoroperacetic acid.
  • It is used as a solvent for NMR and mass spectroscopy analysis.
  • It is used as adhesives and sealant chemicals.

Safety Measures

  • Extremely corrosive to eyes and skin
  • Harmful when it is swallowed.

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