Difference between Conservative and Semiconservative Replication

Conservative Replication

The DNA replicates itself to make multiple copies in this process. In conservative replication, two DNA copies are produced from one original DNA, which serves as a template. Out of these two, one is entirely new DNA, and the other is made of old DNA strands. This kind of DNA replication is not biologically significant.

Semiconservative Replication

It produces two copies of DNA in such a way that one strand is from the original DNA and the other one is a new strand. Usually, the new strand modifies according to the template strand. This method is beneficial to the DNA repair mechanism. It was Watson and Crick who proposed this widely accepted replication model.

Semiconservative Replication

Difference between Conservative and Semiconservative Replication

Conservative Replication

Semiconservative Replication

It produces one new DNA and one old DNA.

It produces two DNA with one new strand and the other strand from the old DNA.

It is not biologically significant.

This replication is biologically significant.

The role of original DNA as a template strand is not clear.

Each strand of the original DNA acts as a template for a new strand.

Frequently Asked Questions on Difference between Conservative and Semiconservative Replication

What is meant by DNA replication?

It is a biological process by which an original DNA replicates itself to produce two similar copies. It is seen as an essential DNA repair mechanism. Here, the DNA strands separate using the helicase enzyme. Then priming of the DNA strand happens. Later with the help of polymerase, nucleotides are added and assembled to form new DNA.

What is dispersive replication?

It is a replication process that also produces two DNA copies from the original DNA. Here, the two DNA products have distinct regions composed of new and original strands. This replication happens in a random fashion.

What is the use of helicase?

The double helix DNA is unwound during the replication process. This is achieved by an enzyme called helicase. The enzyme moves along the DNA backbone, and helps to unpack the genetic material.

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