Difference Between Lytic and Lysogenic Cycle

Lytic and Lysogenic cycles are the method of viral multiplication. Lytic cycle, relatively more common, is a method of viral multiplication wherein the virus infects a host cell and uses its metabolism to multiply and then destroys the host cell completely. Lysogenic cycle, a rarer method of viral reproduction, depends largely upon the lytic cycle. In this method, the virus integrates its genetic information with that of the host and becomes dormant and lets the host multiply and continue its normal activities. Although similar at times, understanding the difference between lytic cycle and lysogenic cycle is important.

Lytic vs Lysogenic Cycle

Lytic Cycle Lysogenic Cycle
The DNA of the virus doesn’t integrate into the host DNA The DNA of the virus integrates into the host DNA
Host DNA hydrolyzed Host DNA not hydrolyzed
Absence of prophage stage Presence of prophage stage
Viral DNA replication occurs independently from the host DNA replication Viral DNA replication occurs along with the host DNA replication
Occurs within a short period of time Takes time
Symptoms of viral replication are evident Symptoms of viral replication not evident
Genetic recombination in the host bacterium not allowed Genetic recombination in the host bacterium allowed
The cellular mechanism of the host cell completely taken over by the viral genome The cellular mechanism of the host cell slightly disturbed by the viral genome

The main difference between the lysogenic cycle and lytic cycle is their influence on the host cell. At BYJU’S, learn more differences like the difference between replication and transcription.

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