IVF, ZIFT, GIFT Solution for Infertility

Table of Contents

• Introduction
• In-Vitro Fertilization (IVF)
• Zygote intrafallopian transfer (ZIFT)
• Gamete Intra-Fallopian Transfer (GIFT)

About 12-15 % of couples of reproductive age are disturbed by infertility. What is the actual reason behind infertility? What are the different infertility treatments? We will discuss IVF, GIFT, and ZIFT in this section.

When a man or woman is incapable to contribute fully to pregnancy even after insecure coitus, it is referred to as infertility. The reason for infertility may be known or unknown. Mostly ovulation variation in women is the main reason for infertility. In males, insufficient sperm production or genetic defects, etc., are the reasons for infertility.

Infertility can be solved with the help of processes like in vitro fertilization (IVF), zygote intra-fallopian transfer (ZIFT), gamete intrafallopian transfer (GIFT) etc.

Assisted reproductive technology (ART) is a collection of medical manipulation methods to circumvent infertility. The methods include gamete intrafallopian transfer (GIFT), in vitro fertilization (IVF), zygote intra-fallopian transfer (ZIFT), embryo transfer (ET), etc. These all methods aim to increase pregnancy probability to its full term. Cost of treatment and time consumption is counted as two disadvantages of ART.

In vitro fertilization is the most commonly used assisted reproductive technology (ART). In vitro fertilization, as its name-fertilization is done by fusing ovum from the female donor and sperm from the male donor outside the body under strict laboratory conditions. This results in a zygote, or famously known as a test-tube baby. After embryo culturing, an embryo is transferred to the uterus of the mother. This method is commonly performed in the case of women with damaged or clogged Fallopian tubes.

Zygote intra-fallopian transfer (ZIFT), also known as Tubal Embryo Transfer is analogous to IVF. ZIFT is an ART procedure where fertilization happens in a laboratory. The thus formed zygote is then conveyed to the Fallopian tube of the mother using laparoscopy. ZIFT proceeds as follows: egg retrieval from ovaries, fertilization, carrying the zygote into the uterine tubes for implantation and further development. ZIFT is not for women with abnormal uterine tubes.

Unlike IVF and ZIFT, GIFT is an in-vivo fertilization procedure where the gametes –sperm and ova are conveyed directly into the fallopian tube. In GIFT, fertilization and zygote formation is more natural as it takes place within the female body. However, this technique is carried out only if there is enough sperm count and at least one fallopian tube is functional. GIFT is an alternative for IVF.

Achievements, accessibility, and easiness of assisted reproductive technologies (ART) have elevated the scope and expectations of infertile couples irrespective of the cause of infertility.

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