When Do Cells Of Multicellular Organisms Proliferate?
Cells of multicellular entities do not proliferate until they are ordered to do so by extracellular, growth factors and survival... View Article
Latest Posts
Is A Cell-surface Receptor For Mitogen A Common Target Of Oncogenic Mutations?
Cell-surface receptors for mitogens are also common targets of oncogenic mutations. The cytoplasmic protein kinase domain that is often found... View Article
What Governs The Proliferation Of Many Cell Types?
The proliferation of several cell types is regulated by mitogens that promote division and by anti-mitogenic factors that inhibit it.... View Article
What Is The General Requirement Of Tumour Formation In Multiple Mitogenic Components?
Tumour formation generally requires mutations in multiple mitogenic components. Simultaneous activation of both Ras and Myc, for example, is far... View Article
How Is Cell Division In Normal Tissues Coordinated?
In normal tissues, cell division is coordinated with cell growth to maintain cell size. The same is generally true in... View Article
What Governs Cell Proliferation In Normal Tissues?
Cell proliferation in normal tissues is governed not only by local mitogens and growth factors but also by survival factors... View Article
Give One Mechanism By Which Cancer Cells Bypass The Hyperproliferation Stress Response.
The hyperproliferation stress response tends to be suppressed in cancer cells, allowing the continued proliferation of cells carrying overactive mitogenic... View Article
Why Is Tumorigenesis Considered To Be Dependent On The Acquisition Of Genetic Instability?
Tumour evolution is driven by the eventual accumulation of mutations. It is unlikely, however, that the rate of spontaneous mutation... View Article
What Is Microsatellite Instability?
About 15% of colon cancers, and a smaller fraction of other cancers, carry mutations in the enzymes responsible for a... View Article
What Does Aneuploidy In Cancer Lead From?
Generally, Aneuploidy in cancer results from chromosomal instability (CIN), which is a rise in the rate of losses or gains... View Article
What Causes Inherited Genetic Diseases Having A Predisposition To Cancer?
Several inherited genetic diseases in which there is a predisposition to cancer are caused by mutations in the cellular systems... View Article
How Might Defective Double-strand Break Repair Lead To Gross Chromosome Rearrangements?
Rearrangements can arise from failures in the repair of double-strand breaks by homologous recombination. As human chromosomes contain so much... View Article
How Harmful Are Non-reciprocal Translocations?
Non-reciprocal translocation could be specifically dangerous if it produces a chromosome with two centromeres (a dicentric chromosome). The two centromeres... View Article
Describe Telomeres Briefly.
Telomeres are the tracts of repetitive DNA found at the ends of chromosomes that are packaged in particular, proteins providing... View Article
What Is Aneuploidy And Tetraploidy In Cancer Cells?
Usually, human cancer cells have unusual numbers of chromosomes, a condition called aneuploidy. The chromosome number in the later stages... View Article
What Mainly Causes Tetraploidy?
Tetraploidy is considered mainly to be caused by failures in cytokinesis. In the mammalian cell cycle, progression from mitosis to... View Article
Write About The Occurrence Of Tetraploidization.
Tetraploidization occurs at a small but significant rate even in normal cells, perhaps as a response to minor defects in... View Article
Can Cancer Tumours Be Cured?
In most cases, Cancer is fatal as it invades tissues and colonizes them, which gradually destroys and disrupts its function.... View Article
What Goals Must Ideal Cancer Treatment Achieve?
The ideal cancer treatment must achieve two goals. First, the treatment must focus specifically on tumour cells and leave normal... View Article
In Antirrhinum two plants with pink flowers were hybridized. The F1 plants produced red, pink and white flowers in the proportion of 1 red, 2 pink and 1 white. What could be the genotype of the two plants used for hybridization? Red flower colour is determined by RR, and white by rr genes?
A) RR B) rr C) Rr D) rrrr Answer: C) Rr Explanation: Antirrhinum or snapdragon shows incomplete dominance. In incomplete dominance... View Article
