How Is Correct Chromosome Attachment Achieved?
Correct chromosome attachment in meiosis, as in mitosis, is thought to be achieved by a trial and error process whereby... View Article
Latest Posts
What Are Monopolies?
In budding yeast, the monopolar attachment of the two sister kinetochores depends on a group of proteins called the monopolins.... View Article
What Mediates The Response To Recombination Defects?
The response to recombination defects is mediated by a recombination checkpoint system that is analogous to the checkpoint systems controlling... View Article
When Does The First And Second Major Regulatory Transition Occur In The Meiotic Program?
The first main regulatory transition of the meiotic program takes place in late G1, when the diploid cell becomes committed... View Article
Where Can Early Recombination Nodules Be Found?
Electron micrographs of the synaptonemal complex disclose that many particles called early recombination nodules are found between the homologs as... View Article
What Is The Main Structural Component Of The Synaptonemal Complex?
The main structural constituent of the synaptonemal complex is a double row of protein filaments bridging the gap between homologs... View Article
What Is The Role Of Crossover Sites?
The role of crossover sites is a significant regulatory event as it regulates the number of chiasmata holding the homologs... View Article
Justify Why Recombination Is Functional In Promoting Homolog Interactions.
Towards the end of leptotene, the homologs are aligned closely by many interaxis bridges which are thought to correspond to... View Article
What Happens To Homologs In The Zygotene And Pachytene?
In zygotene, the homologs come in proximity, to a distance of about 100 nm, in a phenomenon called synapsis. An... View Article
What Happens In The Phase Of Leptotene To The Duplicated Sister Chromatids?
Meiotic DNA recombination comes along with distinct modifications in the structure of the chromosomes that are prominent readily when viewed... View Article
What Leads To The Expansion Of The D-loop?
At some sites which are designated to become crossovers, a different sequence of events unfolds. The first detectable step in... View Article
When Does Meiotic Recombination Begin?
Meiotic recombination begins when both strands of the DNA double helix are cleaved at many locations by the enzyme Spo11.... View Article
What Are The Outcomes Of The Meiotic Recombination?
There are two main outcomes – Either a non-crossover event which aids in facilitating homolog pairing, however, it does not... View Article
What Happens To Homologous Chromosomes In The Meiotic Prophase?
In the meiotic prophase, homologous chromosomes where each is identified by a sister-chromatid pair—become linked together in preparation for their... View Article
What Is Germline In Multicellular Entities?
In multicellular organisms, entry into the meiotic program occurs only in a small population of cells, called the germline, which... View Article
What Are Aneuploid Cells?
Defects in the meiotic chromosome segregation are infrequent in most of the entities however, more frequent in humans, as they... View Article
How Can Sister Chromatids Be Bi-oriented On The Second Meiotic Spindle?
Although homologs are separated, cohesion between sister-chromatid pairs is maintained at the centromeres throughout the first meiotic division. Hence, sister... View Article
Why Do Chiasmata Hold Homologs Together In Meiosis I?
Chiasmata hold homologs together in meiosis I only as the sister-chromatid arms distal to the chiasmata (that is, on the... View Article
What Happens To The Homolog Pairs After The Meiotic Prophase?
After the meiotic prophase, homolog pairs become bi-oriented on the first meiotic spindle. As each homolog comprises two sister chromatids,... View Article
What Happens In Homolog Pairing?
The events of the meiotic prophase are accompanied by chromosomal changes that are visible under the microscope. In the early... View Article
