The rate of replication in eukaryotes is ~50 nucleotides per second. Replication in eukaryotes occurs bidirectionally from many origins.... View Article
The main function of DNA helicase is to separate two strands of DNA for replication. DNA polymerase is the main enzyme that polymerises the DNA... View Article
Telomerase is an enzyme, which adds TTAGGG repeats to the telomeres and gives them stability and reverses telomere shortening. Telomeres are the... View Article
The replication fork is the area of DNA, where the actual process of replication is occurring at a moment. It resembles the structure of the... View Article
Yes, DNA replicates in both mitosis and meiosis. In meiosis, the cell undergoes two divisions, i.e. meiosis I and II. Meiosis I is reduction... View Article
DNA replication occurs before mitosis as well as meiosis. DNA replication occurs during the S phase of the cell cycle. During mitosis or M phase... View Article
Yes, DNA replication occurs at the interphase, during S-stage of the cell cycle. The cell cycle consists of 4 stages, they are G1, S, G2 and M.... View Article
The DNA replication occurs at the synthesis phase of the cell cycle. The cell cycle is regulated at each stage. If DNA replication does not... View Article
Okazaki fragments are necessary for the replication of both strands simultaneously. As DNA polymerase can only add nucleotides in 5’→3’ direction... View Article
DNA polymerase can synthesise new strands in only 5’→3’ direction so the template strand of the DNA having 5’→3’ polarity is synthesized... View Article
DNA, which consists predominantly of the G-C base pairs is the hardest to separate as this base pair is bonded by three hydrogen bonds. The two... View Article
DNA polymerase cannot initiate replication, it can only add nucleotides to the 3' OH group of the last nucleotide. It requires a primer to... View Article
The unit of replication is replisome, which is a large protein complex and carries out the replication process. Replisome is composed of many... View Article
DNA replication is not perfect, there occurs error after every 104 to 105 nucleotides added. The integrity of the genome is maintained by the... View Article
Once the DNA is replicated, we get two new DNA molecules each with one old and one newly formed strand. Cell can now undergo division and each... View Article
Yes, DNA replication is a natural process of DNA duplication at the time of cell division. It is an essential process so that each daughter cell... View Article
The three primary components of DNA are nitrogenous bases (adenine, guanine, thymine and cytosine), deoxyribose sugar and phosphate group. DNA... View Article
DNA replication occurs in the interphase nuclei of eukaryotic cells. DNA replication occurs before mitosis at the S-stage (synthesis) of the cell... View Article
DNA replication occurs at the S-stage of the cell cycle. DNA replication is initiated by unwinding a short stretch of DNA by initiator protein... View Article
DNA replication occurs in the 5’ to 3’ direction. DNA polymerase can only add nucleotides to the 3’ OH group of the growing DNA strand, this is... View Article