Difference between Allograft and Autograft

Allograft and autograft are two types of grafts that are used in transplantation in organisms. Allotransplantation is the transplantation of a body organ, muscle or graft from one person (genetically non-identical) of the same species to another. The graft that is transplanted is known as the allograft.

On the other hand, autotransplantation is the transplantation of a body graft from one location to another in the same person’s body. The graft is known as an autograft.

Let us look at more such differences between allograft and autograft in the table below.

Allograft

Autograft

Definition

Allograft is a tissue taken from another person.

Autograft is a tissue taken from the same person’s body.

Source of Tissue

The tissue comes from a donor’s body.

The tissue is taken from the patient itself.

Reliability

It is less reliable.

It is more reliable.

Chances of Infection

The chances of infection is high as the graft comes from a donor body.

The chances of infection is low.

Chances of Rejection

The chances of rejection are high.

The chances of rejection are low.

Advantages

  • It is easily available in tissue banks.
  • There is one less surgery in this method.
  • The graft can be taken from a cadaver as well.
  • The chances of rejection are low as the graft is used from the same body.
  • There are less chances of infection as well.

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Frequently Asked Questions

What is the difference between allograft and xenograft?

Allograft is the transplantation of a graft from one person to another of the same species, for example: human to human. On the other hand, xenograft is the transplantation of a body graft from one organism to a totally different organism, for example: pig to human.

What is the difference between allograft and isograft?

Allograft is a graft taken from a genetically non identical person of the same species, whereas isograft is a graft taken from a genetically identical person, that is a twin.

Are autograft and xenograft the same?

No, autograft is the graft transfer from one location to another in a person’s body whereas, xenograft is the transfer of graft from one species to another species.

What are the four types of grafts?

The four types of grafts are: (i) allograft (ii) autograft (iii) xenograft (iv) isograft.

What are the types of allograft rejection?

There are three types of allograft rejection:

  • Hyperacute: The rejection of donor graft within a few minutes to hours.
  • Acute: The rejection of the donor graft within a few weeks to months.
  • Chronic: It is a long term rejection which appears after years of transplant.

What are the most donated organs?

According to the CDC, the kidney, lungs, heart and liver are the most donated organs.

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