Haemophilia is a bleeding disorder, which is caused due to deficiency of blood clotting factors. Haemophilia A is caused due to deficiency of... View Article
Blood clotting factors are named in Roman numerals, e.g. I, II, VIII, IX, etc. Factor IX is also called the Christmas factor. Deficiency of... View Article
Haemophilia is an X-linked recessive disorder. Haemophilia is more common in males because they have only one X-chromosome and defect in one copy... View Article
If two alleles of a gene are A and a, then p and q represent the frequencies of dominant and recessive alleles, respectively. Further reading:... View Article
Inbreeding increases homozygosity. It increases the risk of offsprings with homozygous recessive alleles, which have deleterious effects.... View Article
Factor 9 or IX is a clotting factor, which is involved in blood clotting. Defect in the gene leading to a deficiency of clotting factor IX causes... View Article
Haemophilia is a sex-linked inherited disorder. It is an X-linked recessive disease. Men with haemophilia genes pass it on to their daughters and... View Article
Haemophilia can be detected before birth by doing prenatal testing such as chorionic villus sampling (CVS) or amniocentesis. Further reading:... View Article
Phenotype frequency is the proportion of individuals showing a particular trait or phenotype in the population. Further reading: Adaptive... View Article
Allele frequencies of a population can be changed by natural selection, gene flow, genetic drift, mutation and genetic recombination. They are... View Article
The two letters in a genotype represent the pair of alleles. The uppercase letter represents the dominant allele and the lowercase letter... View Article
Haemophilia is a genetic disorder, which is caused due to mutation in the gene coding for clotting factors. Haemophilia A and B are caused due to... View Article
Mutations may occur due to error at the time of DNA replication or due to external factors such as UV radiations, tobacco smoking, etc. Further... View Article
Haemophilia is rare in women due to its inheritance pattern. It is an X-linked recessive trait. Females have two copies of the X chromosome and... View Article
Although 99.9% of the genome is the same in all people, yet every individual has unique DNA, which accounts for their unique characteristics and... View Article
Phenotype frequency for a particular phenotype is calculated by dividing the number of individuals of the particular phenotype by the total... View Article
Humans share around 98.7 percent genome with chimpanzees. Bonobos are also closest to humans and are very similar to chimpanzees. They share 99.6... View Article
The four evolutionary forces that would disrupt population in the equilibrium are gene flow, genetic drift, mutation and natural selection.... View Article
Frequency of recessive allele can be calculated using the Hardy-Weinberg equilibrium equation. The frequency of the recessive allele is taken as... View Article