Polygenic inheritance refers to the inheritance, where multiple genes affect a single phenotypic trait such as height, eye colour, skin colour,... View Article
Mutation refers to any change in the DNA sequence, which leads to altered genotype and phenotype. Further reading: Chromosome Structure... View Article
There are various diseases caused by point mutation such as sickle cell anaemia, colour blindness, Tay Sachs disease, cancer, etc. Further... View Article
When there is a change in the single base pair in the DNA, it is called a point mutation. Point mutation occurs mostly due to substitution.... View Article
Sickle cell anaemia is a classic example of point mutation. Here, single base substitution at the sixth codon of the beta-globin chain from GAG... View Article
Epistasis is the interaction between non-allelic genes found at different loci. Here one gene masks the phenotypic effect of another gene present... View Article
Yes, albinism is an example of pleiotropy. It is caused by a defect in the single gene, i.e. tyrosinase gene and causes multiple phenotypic... View Article
An example of epistasis is a gene for baldness over a gene for hair colour in humans. Further reading: Polygenic Inheritance Chromosome... View Article
Skin colour, eye colour, height, etc. are examples of polygenic inheritance. Further reading: Polygenic Inheritance Chromosome Structure... View Article
Height is a polygenic trait, it is controlled by at least 3 genes. Individual height varies and has a wide range of possibilities. Further... View Article
Phenylketonuria is an example of pleiotropy. It is a metabolic disorder, which occurs due to a defective gene for the enzyme phenylalanine... View Article
Pleiotropy refers to the single gene having multiple phenotypic expressions, whereas polygenic inheritance refers to a trait being controlled by... View Article
Pleiotropy is a condition in which a single gene has multiple phenotypic expressions. E.g. Phenylketonuria is caused by a single gene defect but... View Article
Yes, phenylketonuria can be detected before birth by doing prenatal tests such as amniocentesis and chorionic villus sampling. Further reading:... View Article
Phenylketonuria is treated by adjusting diet by limiting the intake of protein, rich in phenylalanine. Further reading: Polygenic Inheritance... View Article
When phenylalanine accumulates, it gets converted into phenyl pyruvic acid and other derivatives. It results in brain damage, seizures and mental... View Article
Phenylketonuria causes irreversible damage to the brain and results in mental retardation. It occurs due to the accumulation of phenylalanine in... View Article
If you have PKU or phenylketonuria, foods rich in phenylalanine should be avoided. People with phenylketonuria cannot metabolise phenylalanine... View Article
Phenylketonuria is an autosomal recessive trait so a diseased child inherits two copies of the defective gene, one from each parent. Further... View Article
