Difference Between Smooth Endoplasmic Reticulum And Rough Endoplasmic Reticulum

First off, let’s find out what an endoplasmic reticulum is: It is a network of membranes present inside the eukaryotic cells. These are responsible for production and transportation of proteins, fats and other important molecules required for the functioning of a cell.

Difference Between Smooth Endoplasmic Reticulum And Rough Endoplasmic Reticulum

All though a very important component of the cell, not every cell has an ER. For instance, RBCs do not have ER. Cells that play an important role in the production of proteins and oils have large amounts of ER. Structurally, there are 2 types of endoplasmic reticulum in a cell. They are rough endoplasmic reticulum and smooth endoplasmic reticulum.

What is the difference between Smooth and Rough Endoplasmic Reticulum?

The most basic difference between Smooth Endoplasmic Reticulum And Rough Endoplasmic Reticulum is the presence of Ribosomes. When ribosomes attach to the surface of an ER, it gives a characteristic rough appearance, hence it is called Rough ER. On the other hand, a smooth ER does not have ribosomes on its surface. The other major difference between Smooth Endoplasmic Reticulum And Rough Endoplasmic Reticulum are summarized below:

Difference Between Smooth And Rough Endoplasmic Reticulum

Smooth Endoplasmic Reticulum

Rough Endoplasmic Reticulum

Absence of ribosomes on its surface

Presence of ribosomes on its surface

Appearance resembles tubes

Appearance resembles sheets or disks

Oil producing cells have a higher ratio of SER

Protein producing cells have a higher ratio of RER

SER is dispersed across the cell

RER is usually attached to the nuclear membrane or present near it

Forms when RER loses its ribosomes

Forms from the nuclear membranes

Conclusion

The most obvious Difference Between Smooth And Rough Endoplasmic Reticulum is the presence of ribosomes. Only the rough endoplasmic reticulum has ribosomes on its surface and that gives it its characteristic rough appearance.

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