Difference Between Smooth Endoplasmic Reticulum And Rough Endoplasmic Reticulum

The endoplasmic reticulum is a network of membranes present inside the eukaryotic cells. These are responsible for the production and transportation of proteins, fats and other important molecules required for the functioning of a cell.

Difference Between Smooth Endoplasmic Reticulum And Rough Endoplasmic Reticulum

Difference Between RER and SER

Although a very important component of the cell, not every cell has an Endoplasmic Reticulum. For instance, RBCs do not have an ER.

Cells that play an important role in the production of proteins and oils have large amounts of ER. Structurally, there are 2 types of endoplasmic reticulum in a cell. They are rough endoplasmic reticulum and smooth endoplasmic reticulum.

Difference between Smooth and Rough Endoplasmic Reticulum

The most basic difference between RER and SER is the presence of Ribosomes. When ribosomes attach to the surface of an ER, it gives a characteristic rough appearance, hence it is called Rough ER. On the other hand, a smooth ER does not have ribosomes on its surface.

The other major difference between Smooth Endoplasmic Reticulum And Rough Endoplasmic Reticulum are summarized below:

Rough Endoplasmic Reticulum (RER) Smooth Endoplasmic Reticulum (SER)
It possesses ribosomes attached to its membrane. It does not have ribosomes on its membrane.
Formed of cisternae and a few tubules. Formed of vesicles and tubules.
It participates in the synthesis of enzymes and proteins. Synthesises glycogen, lipids and steroids.
It helps in the formation of lysosomes. Gives rise to sphareosomes.
It is internal and connected with the nuclear envelope. It is peripheral and may be connected to plasmalemma.
Ribophorins help in the attachment to the ribosomes. Devoid of Ribophorins.
It might develop from the nuclear envelope. Develops from Rough Endoplasmic Reticulum.
Provides biochemical for Golgi apparatus. Provides vesicles for cis-face of Golgi apparatus.

The most obvious Difference Between Smooth And Rough Endoplasmic Reticulum is the presence of ribosomes. Only the rough endoplasmic reticulum has ribosomes on its surface and that gives it its characteristic rough appearance.

For more details on the difference between the RER and SER, keep visiting BYJU’S website or download BYJU’S app for further reference.

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