Nucleoplasm is a type of protoplasm that is composed of thick fluid and constitutes chromatin fibers made up of DNA and usually found in the nucleus of the eukaryotic cells. This fluid contains primarily water, dissolved ions, and a complex mixture of molecules. Its primary function is to act as a suspension medium for the organelles of the nucleus.


The nucleoplasm includes the chromosomes and nucleoli. Many substances such as nucleotides and enzymes, which direct activities that take place in the nucleus are dissolved in the nucleoplasm. The soluble, liquid portion of the nucleoplasm is called the nucleosol or nuclear hyaloplasm.

Nucleoplasm also called nuclear sap or karyoplasm. Other functions of nucleoplasm include the maintenance of nuclear shape and structure, and the transportation of ions, molecules, and other substances important to cell metabolism and function.

It is a highly gelatinous, sticky liquid that supports the chromosomes and nucleoli. A soluble, fluid component of the nucleoplasm is called the nuclear hyaloplasm.

Nucleoplasm is found inside the nucleus and resembles cytoplasm is some aspects. It is composed mostly of water, nucleoplasm also has an array of complex components.

However, the difference between cytoplasm and nucleoplasm is that nucleoplasm consists of such materials including nucleotide making them useful in the preparation of RNA and DNA and also the enzymes that influence the building reactions of DNA and RNA.

All these substances and components present inside the cell membrane together are considered as nucleoplasm and hence it comprises of the nucleus, cell fluids, and the organelles.

The principal function of the nucleoplasm is to program as a suspension substance for the organelles inside the nucleus. It also helps to maintain the shape and structure of the nucleus and plays an important role in the transportation of materials that are vital to cell metabolism and function.

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