Difference Between Purines and Pyrimidines

Difference Between Purines And Pyrimidines

Purines and pyrimidines are both organic compounds that take part in the synthesis of DNA and RNA. They are nitrogenous bases that make up the two different nucleotides in DNA and RNA. Purines (adenine and guanine) are two-carbon nitrogen ring bases while pyrimidines (cytosine and thymine) are one-carbon nitrogen ring bases. Given below in a tabular column are the differences between Purines and Pyrimidines.

Purine vs Pyrimidine

Purines Pyrimidines
Purine is a heterocyclic aromatic organic compound composed of a pyrimidine ring fused with imidazole ring. Pyrimidine is a heterocyclic aromatic organic compound that is composed of carbon and hydrogen.
It comprises adenine and guanine as nucleobases. It comprises Cytosine, thymine, uracil as nucleobases
It consists of two hydrogen-carbon rings and four nitrogen atoms It consists of one hydrogen-carbon ring and two nitrogen atoms
The melting point of purine is 214 °C The melting point of pyrimidine is 20-22 °C
Catabolism results in the production of uric acid Catabolism produces carbon dioxide, beta amino acids and ammonia

Both purine and pyrimidine have same functions. They are vital for the production of DNA and RNA, starch and proteins. They also serve as a form of energy for cells. They regulate enzymes and are necessary for cell signalling.

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