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Question

What solvent is best for E2 reaction?


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Solution

E2 reaction:

  • E2 mechanism or reaction refers to a bimolecular elimination which is basically a one-step mechanism and is usually favored by strong bases.
  • E2 reaction is preferred by polar solvents (polar protic) that are capable of Hydrogen bonding.
  • Some of the common examples of polar protic solvents include alcohol and water.
  • Let, us have a look at the mechanism for E2 reaction:

Hence, the solvent that we use here is a “polar protic solvent”.like water, ethanol, methanol, ammonia, acetic acid, etc,


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