Which of these will produce the highest yield in Friedel-Craft’s reaction?
Open in App
Solution
The correct option is C
The explanation for the correct option:
Option C:
Here, the group's M effect causes an electron displacement from the ring to the group.
The ring is quite inactive.
In the Friedel-Crafts process, we employ as a catalyst.
Because both phenol and aniline will produce the deactivated ring, none undergo the Friedel-Craft process.
Due to the chlorine's +M action, electrons are displaced from the group to the ring.
As a result, the Friedel-Craft process will generate the maximum yield when chlorobenzene is used.
The explanation for the incorrect options:
Options A, B, and D:
Only aniline and phenol have substantial +R effects, but aniline is a Lewis base, which means it can react with a Lewis acid introduced during the reaction.
As a result, in Friedel-reaction, Craft's phenol produces the lowest yield.