Question

With respect to drug-enzyme interaction, identify the wrong statement.

• A. Allosteric inhibitor competes with the enzyme's active site
• B. Competitive inhibitor binds to the enzyme's active site
• C. Non-competitive inhibitor binds to the allosteric site
• D. Allosteric inhibitor changes the enzyme's active site

Answer 1

The correct option is A Allosteric inhibitor competes with the enzyme's active site

Answer: (a)
Allosteric inhibitors does not compete with substrate for enzymes's active site. It binds to the allosteric site and changes the shape of the active site in such a way that substrate cannot recognise it. Such inhibitor is known as Non-competitive inhibitor.
Hence, statement (a) is wrong.