Question

Are condensins required for sister-chromatid resolution?

Answer 1

Condensins

1. Large protein complexes that modulate the assembly and segregation of chromosomes during meiosis and mitosis are called condensins.
2. Sister chromatids are two identical copies of a chromosome. They are connected by a centromere.
3. Condensin helps in the segregation of sister chromatids during anaphase and improves the stability of the genome.
4. Condensins are required for sister-chromatid resolution.
5. Mutations in condensin proteins cause defects in chromosome segregation and are linked to the formation of tumors.