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Question

Are nucleotides acidic or basic?


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Solution

Acid:

  1. Any hydrogen-containing substance that is capable of donating a proton (hydrogen ion) to another substance.
  2. They have a pH of <7.
  3. Example- H2SO4, HCl, CH3COOH, etc.

Base:

  1. A molecule or ion that is capable of accepting a hydrogen ion from an acid.
  2. They have a pH of >7.
  3. Example- NaOH, Ca(OH)2, etc.

Nucleotides:

  1. Organic molecules with a basic composition of a nitrogenous base, pentose sugar, and phosphate.
  2. DNA and RNA are polynucleotides. They contain a chain of nucleotides monomers with different nitrogenous bases.
  3. They are acidic in nature because of phosphate groups.
  4. The phosphate group has hydrogen which exits by leaving behind a negative charge on it when needed hence it exhibits traits of being acidic.

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