Question

How does the distance between two genes affect crossover frequencies?

Answer 1

Crossover frequency:

1. Recombination frequency is a measure of genetic linkage that is used to create hereditary linkage maps.
2. A centimorgan (cM) is a unit that represents a 1% recombination frequency. We can estimate the hereditary distance between two loci based on their recombination frequency in this way.
3. A twofold crossover is improbable if the loci we're looking at are quite close (less than 7 cM).
4. The possibility of a double crossover increases as distances grow.
5. Alfred Sturtevant explained the frequency of recombination between gene pairs on the same chromosome.
6. He showed that recombination frequency between gene pairs is a measure of the distance between the genes, and that this distance is inversely proportional to the recombination frequency.