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Question

How many short polypeptide chains are seen in insulin?


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Solution

Human insulin:

  1. Insulin is made up of two short polypeptide chains, A and B, that are joined together by disulfide bridges.
  2. Human insulin is made up of 51 amino acids that are organized into two polypeptide chains: A (21 amino acids) and B (30 amino acids).
  3. Insulin is used to treat diabetes and is produced by a pro–hormone found in humans.
  4. Because prohormones contain an extra stretch known as the C peptide, they must be processed to become fully mature and functional hormones.
  5. C peptide is not found in mature insulin and is removed during the maturation process that converts proinsulin to insulin.

Welcome to the Living World: Biotechnology and Its Applications - Notes | Class  12 | Part 2: Applications in Medicine


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