Atrial Natriuretic Peptide (ANP):
- It is a small peptide released by the heart when atrial stretch and increased systemic blood pressure is experienced.
- It then stimulates vasodilation of the afferent arteriole of the glomerulus.
- ANP is the first hormone that was isolated from the heart and acts as a hypotensive and potent diuretic/natriuretic factor.
- Atrial Natriuretic peptide comprise of an intra-molecular ring structure, that is associated with two cysteine residues and C-terminal and N-terminal extensions from them.