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Question

Is ANP a diuretic?


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Solution

Atrial Natriuretic Peptide (ANP):

  1. It is a small peptide released by the heart when atrial stretch and increased systemic blood pressure is experienced.
  2. It then stimulates vasodilation of the afferent arteriole of the glomerulus.
  3. ANP is the first hormone that was isolated from the heart and acts as a hypotensive and potent diuretic/natriuretic factor.
  4. Atrial Natriuretic peptide comprise of an intra-molecular ring structure, that is associated with two cysteine residues and C-terminal and N-terminal extensions from them.

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