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Question

Is haemophilia a pleiotropy?


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Solution

Haemophilia:

  1. Pleiotropy is the phenomenon in which one locus impacts two or more phenotypic traits that appear to be unrelated to one another.
  2. No, haemophilia is not a pleiotropic gene.
  3. Haemophilia is an inherited bleeding disorder marked by low or absent amounts of clotting factors, which prevent or impair blood coagulation.
  4. A classic example of pleiotropy is sickle cell anaemia.
  5. This is caused by the gene HbS.

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