Question

What are some properties of polyclonal antibodies?

Answer 1

Polyclonal antibodies:

1. Polyclonal antibodies (PAbs) are a collection of antibodies released by many B cell lineages.
2. These antibodies are made up of immunoglobulin molecules that react to a specific antigen, each of which recognizes a different epitope on the antigen.
3. The portion of an antigen known as an epitope, also known as an antigenic determinant, is recognized by the immune system, more specifically by antibodies, B cells, or T cells.
4. Polyclonal antibodies have a number of beneficial properties, including the following:
   1. They frequently find a number of epitopes.
   2. As a result, they are more tolerant of modest variations in antigen nature.
   3. These are the best options for detecting denatured proteins.
   4. Can be produced in a variety of species (sheep, goat, rabbit, chicken, donkey), giving the experimental designer a wide range of alternatives.