Stimulates the secretion of bicarbonate-rich pancreatic fluid.
Secretin enters the intestinal lumen and stimulates bicarbonate secretion, ultimately neutralizing gastric H+, which plays an essential role in fat digestion by creating a more neutral environment.
Secretin is released by acid in the duodenum and stimulates pancreatic fluid and bicarbonate secretion, leading to the neutralization of acidic chyme in the intestine.
secretin also inhibits the secretion of gastric acid from the stomach’s parietal cells.