Question

What does the loss of tumour suppressor gene function necessitate?

Answer 1

Tumor suppressor gene:

1. It's a gene that codes for tumor suppressor protein as the name says it controls the cancer formation in cells.
2. Also controls cell division and cell growth.

Loss of tumor suppressor gene leads to:

1. Mutation in tumor suppressor gene leads to cancer
2. The loss of tumor suppressor gene function necessitates the inactivation of both alleles of the gene.
3. Reasons for inactivation of tumor suppressor gene include Small deletions or simple point mutations.