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Question

What happens in the prophase of mitosis?


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Solution

Stages of mitosis:

  1. Based on the physical condition of the chromosomes and spindle, mitosis is thought to have five stages.
  2. Prophase, prometaphase, metaphase, anaphase, and telophase are the different stages of mitosis.
  3. Cytokinesis is the final physical cell division that occurs after telophase and is thus sometimes regarded as a sixth mitotic phase.

Prophase:

  1. Mitosis starts during prophase when chromosomes recruit condensin and begin a condensation process that will last until metaphase.
  2. During prophase, cohesin is mainly eliminated from the arms of sister chromatids in most species, allowing the individual sister chromatids to be resolved.
  3. However, cohesin is preserved at the centromere, the most restricted portion of the chromosome.
  4. The spindle begins to develop during prophase when the two pairs of centrioles shift to opposing poles and microtubules begin to polymerize from the duplicated centrosomes.

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