Hydrophobic patch: It is defined as a cluster of adjacent non-polar atoms that are considered accessible on a particular protein surface.
Hydrophibity due to certain amino acids protects the protein molecule to dissolve in polar solvents like water.
However hydrophobic proteins have as hydrophobic interactions that are important for protein folding.
The hydrophobic patch forms the interior core of the proteins.
This is important for keeping the protein stable and biologically active, as it can reduce the surface area of the protein and reduce unwanted interactions with water.
