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Question

What is the role of zona pellucida in implantation?


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Solution

The zona pellucida is a thick extracellular coat that surrounds all mammalian eggs and preimplantation embryos.

Role of zona pellucida in implantation:

1. It provides physical support for the blastomeres, inhibition of inappropriate tubal implantation, and protection from the maternal immune system.

2. It acts as a barrier to sperm–oocyte interaction, polyspermy, and embryo uterine interaction before implantation.


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