What is the role of zona pellucida in implantation?
The zona pellucida is a thick extracellular coat that surrounds all mammalian eggs and preimplantation embryos.
Role of zona pellucida in implantation:
1. It provides physical support for the blastomeres, inhibition of inappropriate tubal implantation, and protection from the maternal immune system.
2. It acts as a barrier to sperm–oocyte interaction, polyspermy, and embryo uterine interaction before implantation.