What Is The Syndrome Of Inappropriate Antidiuretic Hormone?

It is a form of hyponatraemia, where the degree of antidiuretic hormone is not appropriate to the volume or osmotic stimuli, almost a reverse of cranial diabetes insipidus. The reason could be categorized into ectopic secretions by tumours specially small cell carcinoma of the lung, tumours, central nervous system disorders, trauma, infection and pulmonary lesions, drugs and infections for instance carbamazepine. There are strict diagnostic criteria such as the need for normovolemia, cardiac and liver function, normal endocrine in urinary osmolality higher than the osmolality of the plasma. Correcting the hyponatraemia to the apt speed of onset in the treatment which eradicates the cause.

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