Question

What mainly causes tetraploidy?

Answer 1

Tetraploidy:

1. It is a chromosomal anomaly in which an individual contains four copies of the same chromosome.
2. This condition is caused due to abnormal cell division in which the chromosomes fail to separate during meiosis.
3. It is generated due to the non-disjunction of sister chromatids during recombination and the chromosomes fail to segregate during gamete formation.
4. In humans, tetraploidy implies that each cell contains up to 32 chromosomes. Most of the pregnancies with tetraploid fetus end in miscarriage or the infant dies immediately after birth.
5. They result in multiple congenital anomalies in the central nervous system, cardiac, and renal system.
6. The fetus fail to thrive and experience delay in development.