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Question

What stimulates Leydig cells interstitial cells to produce testosterone?


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Solution

Testosterone:

  1. Testosterone is a sex hormone produced by the testes.
  2. Testosterone is an androgen, which means it controls the development of masculine traits.
  3. It operates in the body by locating and attaching to certain androgen receptors.
  4. When guys' bodies do not create enough testosterone, it can lead to decreased muscular mass, poor facial hair growth, a lack of sex desire, a lack of body hair, and erectile dysfunction.

Stimulation of Leydig cells:

  1. Leydig cells in the interstitial compartment produce testosterone.
  2. Luteinizing hormone (LH) promotes the secretion of testosterone by interstitial cells.
  3. When LH binds to its unique Leydig cell membrane receptor, testosterone is generated.
  4. The anterior pituitary gland secretes LH.
  5. GnRH produced by the hypothalamus increases the pituitary gland's LH secretion.

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