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Question

What will be the sequence of mRNA produced by the following stretch of DNA? 3' ATCGGTTAAC 5' template strand, 5' TAGCCAATTG 3' in coding strand.


A

5’ AUCGGUUAAC 3’

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B

3’ GUUAAGGCAU 5’

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C

3’ GUUAACCGAU 5’

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D

5’ UAGCCUUAAC 5’

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Solution

The correct option is C

3’ GUUAACCGAU 5’


The correct option is C.

Explanation of the correct option:

  1. The act of copying information from a strand of DNA into a fresh messenger RNA molecule is called transcription (mRNA).
  2. DNA preserves genetic material as a reference or template safely and permanently in the cell nuclei.
  3. The DNA strand with the polarity 3′ → 5′ acts as a template for RNA polymerase during transcription.
  4. The other DNA strand which has the polarity 5′ → 3′ is known as the coding strand and has the same sequence as RNA except for thymine, which is replaced by uracil in RNA.

Explanation of the incorrect options:

Option A:

The sequence of mRNA produced by 3' ATCGGTTAAC 5' template strand, 5' TAGCCAATTG 3' stretch of DNA in coding strand will be 5’ AUCGGUUAAC 3’.

Option B:

The sequence of mRNA produced by 3' ATCGGTTAAC 5' template strand, 5' TAGCCAATTG 3' stretch of DNA in coding strand will be 3’ GUUAAGGCAU 5’.

Option D:

The sequence of mRNA produced by 3' ATCGGTTAAC 5' template strand, 5' TAGCCAATTG 3' stretch of DNA in coding strand will be 5’ UAGCCUUAAC 5’.

Final answer: The sequence of mRNA produced by 3' ATCGGTTAAC 5' template strand, 5' TAGCCAATTG 3' stretch of DNA in coding strand will be 3’ GUUAACCGAU 5’.


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