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Question

When Does The First And Second Major Regulatory Transition Occur In The Meiotic Program?


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Solution

Meiosis:

  1. It is a form of cell division that takes place in the germ cells.
  2. It takes place in two phases: reductional division (meiosis II) and equational division (meiosis II).
  3. It results in the formation of four daughter cells with copies of the parental genome.

The following transitions take place:

  1. The first main regulatory transition of the meiotic program takes place in late G1 when the diploid cell becomes committed to the meiotic S phase.
  2. The second main transition takes place at the entry into the meiosis I or first meiotic division.
  3. Progression through such a checkpoint results in the separation of centrosomes or spindle pole bodies (already duplicated during the meiotic S phase and prophase) and the assembly of the first meiotic spindle.


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