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Question

Where is pepsinogen produced?


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Solution

Pepsinogen:

  1. Pepsinogen, an inactive zymogen, is secreted by gastric main cells.
  2. Hydrochloric acid is secreted by parietal cells in the stomach lining, lowering the stomach's pH.
  3. When pepsinogen is exposed to HCl, it is transformed into pepsin (the active enzyme), a proteolytic enzyme.

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