Question

Which enzyme is responsible for the conversion of inactive fibrinogens to fibrins?

Answer 1

Blood clotting :

1. Blood clotting is also called coagulation. The process of coagulation starts when some tissue is injured and bleeding is started.
2. Injured tissue releases a clotting factor that stimulates Extrinsic and Intrinsic Pathways.
3. The clotting factor released from damaged tissue also initiates the conversion of the inactive zymogen, prothrombin into an active enzyme known as thrombin.
4. Enzyme thrombin catalyzes the conversion of soluble plasma proteins fibrinogen into insoluble fibrous protein fibrin.
5. Fibrin makes a mesh-like structure around the platelet plug made initially and the blood cells are trapped in this mesh to form a clot.
6. After the complete repair of the damaged region, the clot is dissolved by the enzyme Plasmin.